uv keeps a global cache of Python packages and built wheels and links them into your environments. It can grow fast across many projects. It’s safe to clean; uv re-downloads or rebuilds what a project needs on the next sync.
Location: ~/.cache/uv
What’s inside
- Wheels and source distributions
- Built packages
- Downloaded Python interpreters (in some setups)
The uv way
uv cache cleanuv cache prune removes only unused entries, if you’d rather keep what current projects use.

Find every folder like this on your Mac
Tidy Mac’s Space Map shows every big folder at its real size, and Apps › Leftovers finds folders left by apps you already deleted.
Frequently asked questions
Can I delete .cache/uv?
Safe: Your Mac or your apps recreate this automatically. Removing it won’t lose anything you made. uv keeps a global cache of Python packages and built wheels and links them into your environments. It can grow fast across many projects. It’s safe to clean; uv re-downloads or rebuilds what a project needs on the next sync.
Where is .cache/uv on my Mac?
~/.cache/uv. In Finder choose Go › Go to Folder and paste the path.
How big does .cache/uv get?
Usually 1 – 20 GB.